P(NIPAM-co-DMAEMA) hydrogel engineering of magnetic nanodiscs for smart delivery of viral vectors under magnetic stimulation
Macchione MA, Donnarumma PR, Hamdan F, Budić I, Gutiérrez-Pineda E, Kocar E, Marković T, Cerullo V, Gregurec D, Moya SE (2026)
Publication Type: Journal article
Publication year: 2026
Journal
Book Volume: 62
Journal Issue: 79
DOI: 10.1039/d6cc04390a
Abstract
Magnetic nanodiscs (MNDs) act as nanoscale heaters under high magnetic fields. Here, MNDs were coated with the positively charged thermoresponsive polymer poly(N-isopropylacrylamide-co-2-(dimethylamino)ethyl methacrylate) (P(NIPAM-co-DMAEMA) and evaluated for adenovirus complexation and magnetothermal release, enabling viral delivery by remote regulation of transfection through thermal modulation of electrostatic interactions.
Authors with CRIS profile
Involved external institutions
CIC biomaGUNE (Centro de Investigación Cooperativa en Biomateriales)
Spain (ES)
Helsingin yliopisto / University of Helsinki
Finland (FI)
University of Zagreb / Sveučilište u Zagrebu
Croatia (HR)
Spain (ES)
Helsingin yliopisto / University of Helsinki
Finland (FI)
University of Zagreb / Sveučilište u Zagrebu
Croatia (HR)
How to cite
APA:
Macchione, M.A., Donnarumma, P.R., Hamdan, F., Budić, I., Gutiérrez-Pineda, E., Kocar, E.,... Moya, S.E. (2026). P(NIPAM-co-DMAEMA) hydrogel engineering of magnetic nanodiscs for smart delivery of viral vectors under magnetic stimulation. Chemical Communications, 62(79). https://doi.org/10.1039/d6cc04390a
MLA:
Macchione, Micaela A., et al. "P(NIPAM-co-DMAEMA) hydrogel engineering of magnetic nanodiscs for smart delivery of viral vectors under magnetic stimulation." Chemical Communications 62.79 (2026).
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