Treatment of Peripartum Depression with Antidepressants and Other Psychotropic Medications: A Synthesis of Clinical Practice Guidelines in Europe
Kittel-Schneider S, Felice E, Buhagiar R, Lambregtse-Van Den Berg M, Wilson CA, Baljak VB, Vujovic KS, Medic B, Opankovic A, Fonseca A, Lupattelli A (2022)
Publication Type: Journal article, Review article
Publication year: 2022
Journal
Book Volume: 19
Article Number: 1973
Journal Issue: 4
Abstract
This study examined (1) the availability and content of national CPGs for treatment of peripartum depression, including comorbid anxiety, with antidepressants and other psychotropics across Europe and (2) antidepressant and other psychotropic utilization data as an indicator of prescribers’ compliance to the guidelines. We conducted a search using Medline and the Guidelines International Network database, combined with direct e-mail contact with national Riseup-PPD COST ACTION members and researchers within psychiatry. Of the 48 European countries examined, we screened 41 records and included 14 of them for full-text evaluation. After exclusion of ineligible and duplicate records, we included 12 CPGs. Multiple CPGs recommend antidepressant initiation or continuation based on maternal disease severity, non-response to first-line non-pharmacological interventions, and after risk-benefit assessment. Advice on treatment of comorbid anxiety is largely missing or unspecific. Antidepressant dispensing data suggest general prescribers’ compliance with the preferred substances of the CPG, although country-specific differences were noted. To conclude, there is an urgent need for harmonized, up-to-date CPGs for pharmacological management of peripartum depression and comorbid anxiety in Europe. The recommendations need to be informed by the latest available evidence so that healthcare providers and women can make informed, evidence-based decisions about treatment choices.
Involved external institutions
University of Belgrade / Универзитет у Београду
Serbia (RS)
Universidade de Coimbra
Portugal (PT)
University of Oslo
Norway (NO)
Universitätsklinikum Würzburg
Germany (DE)
University of Malta
Malta (MT)
University of Southern Denmark / Syddansk Universitet
Denmark (DK)
Erasmus University Medical Center (MC)
Netherlands (NL)
King’s College London
United Kingdom (GB)
University Clinical Centre of the Republic of Srpska
Bosnia And Herzegovina (BA)
Serbia (RS)
Universidade de Coimbra
Portugal (PT)
University of Oslo
Norway (NO)
Universitätsklinikum Würzburg
Germany (DE)
University of Malta
Malta (MT)
University of Southern Denmark / Syddansk Universitet
Denmark (DK)
Erasmus University Medical Center (MC)
Netherlands (NL)
King’s College London
United Kingdom (GB)
University Clinical Centre of the Republic of Srpska
Bosnia And Herzegovina (BA)
How to cite
APA:
Kittel-Schneider, S., Felice, E., Buhagiar, R., Lambregtse-Van Den Berg, M., Wilson, C.A., Baljak, V.B.,... Lupattelli, A. (2022). Treatment of Peripartum Depression with Antidepressants and Other Psychotropic Medications: A Synthesis of Clinical Practice Guidelines in Europe. International Journal of Environmental Research and Public Health, 19(4). https://doi.org/10.3390/ijerph19041973
MLA:
Kittel-Schneider, Sarah, et al. "Treatment of Peripartum Depression with Antidepressants and Other Psychotropic Medications: A Synthesis of Clinical Practice Guidelines in Europe." International Journal of Environmental Research and Public Health 19.4 (2022).
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