Whispering gallery mode laser: towards the deep and turbid tissue optical sensing

Ni D, Klämpfl F, Schmidt M, Hohmann M (2025)

Publication Type: Conference contribution

Publication year: 2025

Journal

Publisher: SPIE

Book Volume: 13317

Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Event location: San Francisco, CA

ISBN: 9781510683822

DOI: 10.1117/12.3041234

Abstract

This study explores the application of whispering gallery mode (WGM) lasers for deep optical sensing in turbid media. Experimental results demonstrate that WGM lasers achieve accurate detection of the resonator diameter when it is deep in a highly scattering medium. Speciffically, a resonator diameter of 261 µm is detectable with low intra-sample variation (<±2%), even when the resonator is placed at 5 mm deep in a scattering medium with a reduced scattering coefficient of 6.3 mm^-1, a value comparable to the reduced scattering coefficient of skin tissues in visible range. In other words, the sample depth exceeds 30 times the transport length while the resolution maintains in micrometer range. As a comparison, the conventional method of optical coherence tomography can only achieve the penetration depth of one transport length.

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How to cite

APA:

Ni, D., Klämpfl, F., Schmidt, M., & Hohmann, M. (2025). Whispering gallery mode laser: towards the deep and turbid tissue optical sensing. In Norbert Linz, Joel N. Bixler, Alex J. Walsh (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. San Francisco, CA, US: SPIE.

MLA:

Ni, Dongqin, et al. "Whispering gallery mode laser: towards the deep and turbid tissue optical sensing." Proceedings of the Optical Interactions with Tissue and Cells XXXVI 2025, San Francisco, CA Ed. Norbert Linz, Joel N. Bixler, Alex J. Walsh, SPIE, 2025.

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