Nature-inspired functional porous materials for low-concentration biomarker detection

Papiano I, De Zio S, Hofer A, Malferrari M, Minguez Bacho I, Bachmann J, Rapino S, Vogel N, Magnabosco G (2023)

Publication Language: English

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2023


DOI: 10.1039/d3mh00553d


sol-gel processes is a key challenge for their application as electrode materials. In this work, colloidal assembly, atomic layer deposition and selective surface functionalization are combined to design conductive inverse opals as an electrode material for novel glucose sensing platforms. An insulating inverse opal scaffold is coated with uniform layers of conducting aluminum zinc oxide and platinum, and subsequently functionalized with glucose oxidase embedded in a polypyrrole layer. The final device can sense glucose at concentrations in the nanomolar range and is not affected by the presence of common interferents gluconolactone and pyruvate. This method may also be applied to different conductive materials and enzymes to generate a new class of highly efficient biosensors.

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Papiano, I., De Zio, S., Hofer, A., Malferrari, M., Minguez Bacho, I., Bachmann, J.,... Magnabosco, G. (2023). Nature-inspired functional porous materials for low-concentration biomarker detection. Materials Horizons.


Papiano, Irene, et al. "Nature-inspired functional porous materials for low-concentration biomarker detection." Materials Horizons (2023).

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