Rapid single-cell physical phenotyping of mechanically dissociated tissue biopsies

Soteriou D, Kubankova M, Schweitzer C, Lopez Posadas R, Pradhan R, Thoma OM, Györfi AH, Matei AE, Waldner M, Distler J, Scheuermann S, Langejuergen J, Eckstein M, Schneider-Stock R, Atreya R, Neurath M, Hartmann A, Guck J (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Nature Biomedical Engineering Nature Research

DOI: 10.1038/s41551-023-01015-3

Abstract

A method for the sequential assessment of the physical phenotypes of suspended cells singularized from tissue biopsies by mechanical dissociation allows for rapid diagnoses.

Authors with CRIS profile

Rocío Lopez Posadas Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Rashmita Pradhan Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Oana-Maria Thoma Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Andrea-Hermina Györfi Department of Medicine 3 – Rheumatology and Immunology Alexandru-Emil Matei Department of Medicine 3 – Rheumatology and Immunology Maximilian Waldner Lehrstuhl für Innere Medizin I Jörg Distler Professur für Molekulare Mechanismen der Organfibrose Markus Eckstein Institute of Pathology Regine Schneider-Stock Professur für Experimentelle Tumorpathologie Raja Atreya Professur für Translationale Immunforschung bei chronisch entzündlichen Darmerkrankungen (Heisenberg-Professur) Markus Neurath Lehrstuhl für Innere Medizin I Arndt Hartmann Lehrstuhl für Allgemeine Pathologie und Pathologische Anatomie

Additional Organisation(s)

FAU Profilzentrum Licht.Materie.Quantentechnologien (FAU LMQ)

Involved external institutions

Max-Planck-Zentrum für Physik und Medizin (MPZPM) DE Germany (DE) Fraunhofer-Institut für Produktionstechnik und Automatisierung (IPA) DE Germany (DE)

How to cite

APA:

Soteriou, D., Kubankova, M., Schweitzer, C., Lopez Posadas, R., Pradhan, R., Thoma, O.-M.,... Guck, J. (2023). Rapid single-cell physical phenotyping of mechanically dissociated tissue biopsies. Nature Biomedical Engineering. https://doi.org/10.1038/s41551-023-01015-3

MLA:

Soteriou, Despina, et al. "Rapid single-cell physical phenotyping of mechanically dissociated tissue biopsies." Nature Biomedical Engineering (2023).

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