Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes

Culemann S, Knab K, Euler M, Wegner A, Garibagaoglu H, Ackermann J, Fischer K, Kienhoefer D, Crainiciuc G, Hahn J, Grüneboom A, Nimmerjahn F, Uderhardt S, Hidalgo A, Schett G, Hoffmann M, Krönke G (2023)


Publication Type: Journal article

Publication year: 2023

Journal

Book Volume: 220

Journal Issue: 6

DOI: 10.1084/jem.20220525

Abstract

The authors show that the anti-inflammatory effects of clodronate liposomes do not result from the depletion of mononuclear phagocytes but from a functional stunning of polymorphonuclear neutrophils. These findings necessitate a critical revision of the current literature on the role of monocytes and macrophages in inflammation.

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APA:

Culemann, S., Knab, K., Euler, M., Wegner, A., Garibagaoglu, H., Ackermann, J.,... Krönke, G. (2023). Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes. Journal of Experimental Medicine, 220(6). https://doi.org/10.1084/jem.20220525

MLA:

Culemann, Stephan, et al. "Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes." Journal of Experimental Medicine 220.6 (2023).

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