A086: Role of synovial macrophage subsets during inflammatory arthritis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.06.2020
End date : 15.12.2022
Extension date: 15.06.2023
Project details
Scientific Abstract
Our preliminary data identified a unique Cx3Cr1-positive macrophage subset that forms a protective barrier around the joint and counteracts inflammation. Accordingly, we will address the developmental origin and differentiation pathways of these specific macrophages and try to understand the molecular basis of their anti-inflammatory properties. Moreover, we will address the relevance of these findings for human diseases such as rheumatoid arthritis.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 3 – Rheumatology and Immunology
Medizinische Fakultät
