Present and future of surface-enhanced Raman scattering

Langer J, De Aberasturi DJ, Aizpurua J, Alvarez-Puebla RA, Auguie B, Baumberg JJ, Bazan GC, Bell SEJ, Boisen A, Brolo AG, Choo J, Cialla-May D, Deckert V, Fabris L, Faulds K, De Abajo FJG, Goodacre R, Graham D, Haes AJ, Haynes CL, Huck C, Itoh T, Ka M, Kneipp J, Kotov NA, Kuang H, Le Ru EC, Lee HK, Li JF, Ling XY, Maier SA, Mayerhofer T, Moskovits M, Murakoshi K, Nam JM, Nie S, Ozaki Y, Pastoriza-Santos I, Perez-Juste J, Popp J, Pucci A, Reich S, Ren B, Schatz GC, Shegai T, Schlucker S, Tay LL, Thomas KG, Tian ZQ, Van Duyne RP, Vo-Dinh T, Wang Y, Willets KA, Xu C, Xu H, Xu Y, Yamamoto YS, Zhao B, Liz-Marzan LM (2020)

Publication Type: Journal article, Review article

Publication year: 2020


Book Volume: 14

Pages Range: 28-117

Journal Issue: 1

DOI: 10.1021/acsnano.9b04224


The discovery of the enhancement of Raman scattering by molecules adsorbed on nanostructured metal surfaces is a landmark in the history of spectroscopic and analytical techniques. Significant experimental and theoretical effort has been directed toward understanding the surface-enhanced Raman scattering (SERS) effect and demonstrating its potential in various types of ultrasensitive sensing applications in a wide variety of fields. In the 45 years since its discovery, SERS has blossomed into a rich area of research and technology, but additional efforts are still needed before it can be routinely used analytically and in commercial products. In this Review, prominent authors from around the world joined together to summarize the state of the art in understanding and using SERS and to predict what can be expected in the near future in terms of research, applications, and technological development. This Review is dedicated to SERS pioneer and our coauthor, the late Prof. Richard Van Duyne, whom we lost during the preparation of this article.

Involved external institutions

CIC biomaGUNE (Centro de Investigación Cooperativa en Biomateriales) ES Spain (ES) Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN) ES Spain (ES) University of Basque Country / Universidad del Pais Vasco (UPV) / Euskal Herriko Unibersitatea (EHU) ES Spain (ES) Victoria University of Wellington NZ New Zealand (NZ) University of Cambridge GB United Kingdom (GB) University of California US United States (USA) (US) Queen's University GB United Kingdom (GB) Technical University of Denmark / Danmarks Tekniske Universitet (DTU) DK Denmark (DK) University of Victoria (UVic) CA Canada (CA) Chung-Ang University (CAU) KR Korea, Republic of (KR) Leibniz Health Technologies DE Germany (DE) The State University of New Jersey (Rutgers) US United States (USA) (US) University of Strathclyde GB United Kingdom (GB) Institució Catalana de Recerca i Estudis Avançats (ICREA) / Catalan Institution for Research and Advanced Studies ES Spain (ES) The University of Liverpool GB United Kingdom (GB) University of Iowa US United States (USA) (US) University of Minnesota (UMN) US United States (USA) (US) Ruprecht-Karls-Universität Heidelberg DE Germany (DE) National Institute of Advanced Industrial Science and Technology / 産業技術総合研究所 (AIST) JP Japan (JP) Chalmers University of Technology / Chalmers tekniska högskola SE Sweden (SE) Humboldt-Universität zu Berlin DE Germany (DE) University of Michigan US United States (USA) (US) Jiangnan University (JU) CN China (CN) Nanyang Technological University (NTU) SG Singapore (SG) Xiamen University CN China (CN) Ludwig-Maximilians-Universität (LMU) DE Germany (DE) Hokkaido University (Hokudai) / 北海道大学 JP Japan (JP) Seoul National University (SNU) / 서울대학교 KR Korea, Republic of (KR) University of Illinois at Urbana-Champaign US United States (USA) (US) Kwansei Gakuin University / 関西学院大学 (Kangaku / 関学) JP Japan (JP) University of Vigo / Universidade de Vigo ES Spain (ES) Freie Universität Berlin DE Germany (DE) Northwestern University US United States (USA) (US) Universität Duisburg-Essen (UDE) DE Germany (DE) National Research Council / Conseil national de recherches Canada CA Canada (CA) Indian Institute of Science Education and Research Thiruvananthapuram (IISER-TVM) IN India (IN) Duke University US United States (USA) (US) Temple University US United States (USA) (US) Wuhan University CN China (CN) Japan Advanced Institute of Science and Technology (JAIST) / 北陸先端科学技術大学院大学 JP Japan (JP) Jilin University (JLU) / 吉林大学 CN China (CN)

How to cite


Langer, J., De Aberasturi, D.J., Aizpurua, J., Alvarez-Puebla, R.A., Auguie, B., Baumberg, J.J.,... Liz-Marzan, L.M. (2020). Present and future of surface-enhanced Raman scattering. ACS nano, 14(1), 28-117.


Langer, Judith, et al. "Present and future of surface-enhanced Raman scattering." ACS nano 14.1 (2020): 28-117.

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