Exposure to flame retardants in European children - Results from the HBM4EU aligned studies.

Van Der Schyff V, Kalina J, Govarts E, Gilles L, Schoeters G, Castano A, Esteban-Lopez M, Kohoutek J, Kukucka P, Covaci A, Koppen G, Andryskova L, Piler P, Klanova J, Jensen TK, Rambaud L, Riou M, Lamoree M, Kolossa-Gehring M, Vogel N, Weber T, Göen T, Gabriel C, Sarigiannis DA, Sakhi AK, Haug LS, Murinova LP, Fabelova L, Tratnik JS, Mazej D, Melymuk L (2023)

Publication Type: Journal article, Review article

Publication year: 2023

Journal

International Journal of Hygiene and Environmental Health Elsevier

Book Volume: 247

DOI: 10.1016/j.ijheh.2022.114070

Abstract

Many legacy and emerging flame retardants (FRs) have adverse human and environmental health effects. This study reports legacy and emerging FRs in children from nine European countries from the HBM4EU aligned studies. Studies from Belgium, Czech Republic, Germany, Denmark, France, Greece, Slovenia, Slovakia, and Norway conducted between 2014 and 2021 provided data on FRs in blood and urine from 2136 children. All samples were collected and analyzed in alignment with the HBM4EU protocols. Ten halogenated FRs were quantified in blood, and four organophosphate flame retardants (OPFR) metabolites quantified in urine. Hexabromocyclododecane (HBCDD) and decabromodiphenyl ethane (DBDPE) were infrequently detected (<16% of samples). BDE-47 was quantified in blood from Greece, France, and Norway, with France (0.36 ng/g lipid) having the highest concentrations. BDE-153 and -209 were detected in <40% of samples. Dechlorane Plus (DP) was quantified in blood from four countries, with notably high median concentrations of 16 ng/g lipid in Slovenian children. OPFR metabolites had a higher detection frequency than other halogenated FRs. Diphenyl phosphate (DPHP) was quantified in 99% of samples across 8 countries at levels ∼5 times higher than other OPFR metabolites (highest median in Slovenia of 2.43 ng/g lipid). FR concentrations were associated with lifestyle factors such as cleaning frequency, employment status of the father of the household, and renovation status of the house, among others. The concentrations of BDE-47 in children from this study were similar to or lower than FRs found in adult matrices in previous studies, suggesting lower recent exposure and effectiveness of PBDE restrictions.

Authors with CRIS profile

Thomas Göen Medizinische Fakultät

Involved external institutions

Masaryk University CZ Czech Republic (CZ) Norwegian Institute of Public Health (NIPH) / Folkehelseinstituttet NO Norway (NO) Slovak Medical University (SMU) / Slovenská zdravotnícka univerzita v Bratislave SK Slovakia (SK) Jožef Stefan Institute SI Slovenia (SI) Flemish institute for technological research / Vlaamse Instelling voor Technologisch Onderzoek (VITO) BE Belgium (BE) Universidad Carlos III de Madrid (UC3M) ES Spain (ES) University of Antwerp / Universiteit Antwerpen BE Belgium (BE) University of Southern Denmark / Syddansk Universitet DK Denmark (DK) French Institute for Public Health Surveillance / Santé publique France FR France (FR) Vrije Universiteit Amsterdam (VU) / University Amsterdam NL Netherlands (NL) Umweltbundesamt (UBA) DE Germany (DE) Aristotle University of Thessaloniki GR Greece (GR)

How to cite

APA:

Van Der Schyff, V., Kalina, J., Govarts, E., Gilles, L., Schoeters, G., Castano, A.,... Melymuk, L. (2023). Exposure to flame retardants in European children - Results from the HBM4EU aligned studies. International Journal of Hygiene and Environmental Health, 247. https://doi.org/10.1016/j.ijheh.2022.114070

MLA:

Van Der Schyff, Veronica, et al. "Exposure to flame retardants in European children - Results from the HBM4EU aligned studies." International Journal of Hygiene and Environmental Health 247 (2023).

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