Interdisciplinary Surgical Therapy of Extremity Soft-Tissue Sarcomas: A Personalized Resection and Reconstruction Algorithm

Osterloh J, Ludolph I, Grützmann R, Meyer A, Lang W, Horch RE, Fechner K, Arkudas A (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Journal of Personalized Medicine MDPI

Book Volume: 13

Article Number: 262

Journal Issue: 2

DOI: 10.3390/jpm13020262

Abstract

Soft-tissue sarcomas (STS) are rare, but potentially life-threatening malignancies. STS can occur anywhere in the human body with the limbs being the most common site. Referral to a specialized sarcoma center is crucial to guarantee prompt and appropriate treatment. STS treatment strategies should be discussed in an interdisciplinary tumor board to involve expertise from all available resources, including an experienced reconstructive surgeon for an optimal outcome. In many cases, extensive resection is needed to achieve R0 resection, resulting in large defects after surgery. Hence, an evaluation of whether plastic reconstruction might be required is mandatory to avoid complications due to insufficient primary wound closure. In this retrospective observational study, we present data of patients with extremity STS treated at the Sarcoma Center, University Hospital Erlangen, in 2021. We found that complications were more frequent in patients who received secondary flap reconstruction after insufficient primary wound closure compared to patients who received primary flap reconstruction. Additionally, we propose an algorithm for an interdisciplinary surgical therapy of soft-tissue sarcomas regarding resection and reconstruction and present two problematic cases to emphasize the complexity of surgical sarcoma therapy.

Authors with CRIS profile

Justus Osterloh Department of Plastic and Hand Surgery Ingo Ludolph Department of Plastic and Hand Surgery Robert Grützmann Department of Surgery Alexander Meyer Department of Vascular Surgery Werner Lang Department of Vascular Surgery Raymund Horch Professur für Plastische Chirurgie und Handchirurgie Katja Fechner Department of Surgery Andreas Arkudas Medizinische Fakultät

How to cite

APA:

Osterloh, J., Ludolph, I., Grützmann, R., Meyer, A., Lang, W., Horch, R.E.,... Arkudas, A. (2023). Interdisciplinary Surgical Therapy of Extremity Soft-Tissue Sarcomas: A Personalized Resection and Reconstruction Algorithm. Journal of Personalized Medicine, 13(2). https://doi.org/10.3390/jpm13020262

MLA:

Osterloh, Justus, et al. "Interdisciplinary Surgical Therapy of Extremity Soft-Tissue Sarcomas: A Personalized Resection and Reconstruction Algorithm." Journal of Personalized Medicine 13.2 (2023).

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