Statistical iterative reconstruction for multi-contrast x-ray micro-tomography
Allner S, Velroyen A, Fehringer A, Pfeiffer F, Noel PB (2015)
Publication Type: Conference contribution
Publication year: 2015
Journal
Publisher: SPIE
Book Volume: 9412
Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Event location: Orlando, FL, USA
ISBN: 9781628415025
DOI: 10.1117/12.2082619
Abstract
Scanning times have always been an important issue in x-ray micro-tomography. To reach high-quality reconstructions the exposure times for each projection can be very long due to small detector pixel sizes and limited flux of x-ray sources. In addition, the required number of projections is a factor which limits a reduction of exposure beyond a certain level. This applies particularly to grating-based phase-contrast computed tomography (PCCT), as several images per projection have to be acquired in order to obtain absorption, phase and dark-field information. In this work we qualitatively compare statistical iterative reconstruction (SIR) and filtered back-projection (FBP) reconstruction from undersampled projection data based on a formalin-fixated mouse sample measured in a grating-based phase-contrast small-animal scanner. The results from our assessment illustrate that SIR offers not only significantly higher image quality, but also enables high-resolution imaging from severely undersampled data in comparison to the FBP algorithm. Therefore, the application of advanced iterative reconstruction methods in micro-tomography entails major advantages over state-of-the-art FBP reconstruction while offering the opportunity to shorten scan durations via a reduction of exposure time per projection and number of angular views.
Involved external institutions
Germany (DE)How to cite
APA:
Allner, S., Velroyen, A., Fehringer, A., Pfeiffer, F., & Noel, P.B. (2015). Statistical iterative reconstruction for multi-contrast x-ray micro-tomography. In Christoph Hoeschen, Despina Kontos, Christoph Hoeschen (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Orlando, FL, USA: SPIE.
MLA:
Allner, S., et al. "Statistical iterative reconstruction for multi-contrast x-ray micro-tomography." Proceedings of the Medical Imaging 2015: Physics of Medical Imaging, Orlando, FL, USA Ed. Christoph Hoeschen, Despina Kontos, Christoph Hoeschen, SPIE, 2015.
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