Retrieving small features in reflection-mode raster-scan optoacoustic mesoscopy (RSOM) using multi-frequency reconstruction
Omar M, Soliman D, Gateau J, Ntziachristos V (2015)
Publication Type: Conference contribution
Publication year: 2015
Journal
Publisher: SPIE
Book Volume: 9323
Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Event location: San Francisco, CA, USA
ISBN: 9781628414134
DOI: 10.1117/12.2076717
Abstract
We developed a reflection-mode, raster-scan optoacoustic mesoscopy system, based on a custom-made ultrasonic detector, with an ultra wide bandwidth of 20-180 MHz. To optimally use this bandwidth, we implemented multi-frequency reconstruction. System characterization reveals a 4 μm axial, and 18 μm transverse resolution, at penetration depths reaching 5 mm. After characterization, the system was applied to image a zebrafish ex vivo, and an excised mouse ear. In the zebrafish, the lateral line, intestines, eyes, and melanocytes are seen, while in the mouse ear, multi-frequency reconstruction recovered the small vessels, otherwise not seen on the image.
Involved external institutions
Technische Universität München (TUM)
Germany (DE)
École supérieure de physique et de chimie industrielles de la ville de Paris (ESPCI Paris)
France (FR)
Germany (DE)
École supérieure de physique et de chimie industrielles de la ville de Paris (ESPCI Paris)
France (FR)
How to cite
APA:
Omar, M., Soliman, D., Gateau, J., & Ntziachristos, V. (2015). Retrieving small features in reflection-mode raster-scan optoacoustic mesoscopy (RSOM) using multi-frequency reconstruction. In Alexander A. Oraevsky, Lihong V. Wang (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. San Francisco, CA, USA: SPIE.
MLA:
Omar, Murad, et al. "Retrieving small features in reflection-mode raster-scan optoacoustic mesoscopy (RSOM) using multi-frequency reconstruction." Proceedings of the Photons Plus Ultrasound: Imaging and Sensing 2015, San Francisco, CA, USA Ed. Alexander A. Oraevsky, Lihong V. Wang, SPIE, 2015.
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