Effects of High-Intensity Aerobic Exercise and Resistance Training on Cardiometabolic Risk in Early-Postmenopausal Women

Hettchen M, von Stengel S, Kohl M, Murphy MH, Shojaa M, Ghasemikaram M, Bragonzoni L, Benvenuti F, Ripamonti C, Benedetti G, Julin M, Risto T, Kemmler W (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Deutsche Zeitschrift für Sportmedizin Süddt. Verl. onpact

Book Volume: 72

Pages Range: 28-35

Journal Issue: 1

DOI: 10.5960/DZSM.2020.449

Abstract

Purpose: The menopausal transition is a critical period in wo-men’s lives. The central aim of the present study was to evaluate the effect of a multimodal exercise protocol on the cardiometa-bolic risk factor potentially related to menopausal transition in early postmenopausal women. Methods: Fifty-four (54) early-postmenopausal women (54.0±1.8 years) were randomly assigned to two groups: (1) exercise group (EG: n=27) which conducted a high intensity aerobic and resistance training three times/week and (2) active control group (CG: n=27) exercising once a week with low exercise inten-sity. Besides bone density, the main variable of this project, the outcome variable in this thesis was also cardiometabolic risk, as summarized by the Metabolic Syndrome (MetS) Z-Score. We applied Intention-to-Treat (ITT) and Per Protocol Analyses (PPA) with multiple imputation and used standardized mean differences to illustrate the effects. Results: After 16 weeks of exercise two participants (EG: n=1; CG: n=1) were lost to follow-up. Effects for the MetS Z-Score were moderate (EG:-0.36±1.36 vs. CG: 0.51±2.28; SMD: 0.47, 95% CI:-0.08 to 1.03), albeit borderline non-significant (ITT: p=.089; PPA: p=.060). Conclusion: The present multimodal exercise protocol just fai-led to affect the MetS Z-Score and its underlying cardiometabolic risk factors. Whether this result can be generalized to the entire cohort of early-postmenopausal women or whether it has to be attributed to the only moderately high exercise intensity during the early weeks of the intervention along with a relatively short intervention period remains to be evaluated.

Authors with CRIS profile

Michael Hettchen Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Simon von Stengel Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Mahdieh Shojaa Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Mansour Ghasemikaram Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Wolfgang Kemmler Lehrstuhl für Medizinische Physik und Mikrogewebetechnik

Involved external institutions

Rizzoli Orthopaedic Institute / Istituto Ortopedico Rizzoli (IRCCS) IT Italy (IT) Laurea University of Applied Sciences FI Finland (FI) Hochschule Furtwangen DE Germany (DE) University of Ulster GB United Kingdom (GB) University of Bologna / Università di Bologna IT Italy (IT)

How to cite

APA:

Hettchen, M., von Stengel, S., Kohl, M., Murphy, M.H., Shojaa, M., Ghasemikaram, M.,... Kemmler, W. (2021). Effects of High-Intensity Aerobic Exercise and Resistance Training on Cardiometabolic Risk in Early-Postmenopausal Women. Deutsche Zeitschrift für Sportmedizin, 72(1), 28-35. https://dx.doi.org/10.5960/DZSM.2020.449

MLA:

Hettchen, Michael, et al. "Effects of High-Intensity Aerobic Exercise and Resistance Training on Cardiometabolic Risk in Early-Postmenopausal Women." Deutsche Zeitschrift für Sportmedizin 72.1 (2021): 28-35.

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