Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese(ii) superoxide dismutase mimic complex

Mathieu E, Bernard AS, Quevrain E, Zoumpoulaki M, Iriart S, Lung-Soong C, Lai B, Medjoubi K, Henry L, Nagarajan S, Poyer F, Scheitler A, Ivanovic-Burmazovic I, Marco S, Somogyi A, Seksik P, Delsuc N, Policar C (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Chemical Communications Royal Society of Chemistry

Book Volume: 56

Pages Range: 7885-7888

Journal Issue: 57

DOI: 10.1039/d0cc03398g

Abstract

A conjugate of a Mn-based superoxide dismutase mimic with a Re-based multimodal probe1_was studied in a cellular model of oxidative stress. Its speciation was investigated using Re and Mn X-fluorescence. Interestingly,1_shows a distribution different from its unconjugated analogue but a similar concentration in mitochondria and a similar bioactivity.

Authors with CRIS profile

Andreas Scheitler Lehrstuhl für Bioanorganische Chemie Ivana Ivanovic-Burmazovic Lehrstuhl für Bioanorganische Chemie

Involved external institutions

PSL Research University / Université de recherche Paris Sciences et Lettres FR France (FR) Argonne National Laboratory US United States (USA) (US) Synchrotron SOLEIL FR France (FR)

How to cite

APA:

Mathieu, E., Bernard, A.-S., Quevrain, E., Zoumpoulaki, M., Iriart, S., Lung-Soong, C.,... Policar, C. (2020). Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese(ii) superoxide dismutase mimic complex. Chemical Communications, 56(57), 7885-7888. https://dx.doi.org/10.1039/d0cc03398g

MLA:

Mathieu, Emilie, et al. "Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese(ii) superoxide dismutase mimic complex." Chemical Communications 56.57 (2020): 7885-7888.

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