Pujales Paradela R (2019)
Publication Status: Published
Publication Type: Journal article, other
Publication year: 2019
Publisher: ROYAL SOC CHEMISTRY
Book Volume: 55
Pages Range: 4115-4118
Journal Issue: 28
DOI: 10.1039/c9cc01204d
Reinforced cross-bridged Ni2+-cyclam complexes were functionalised with pendant arms containing both amide protons and CF3 groups that lead to a dual H-1/F-19 response. The resulting complexes possess very high inertness favourable for MRI applications. The paramagnetism of the Ni2+ ion shifts the amide resonance 56 ppm away from bulk water favouring the chemical exchange saturation transfer (CEST) effect and shortening the acquisition times in F-19 magnetic resonance imaging (MRI) experiments, thus enhancing the signal-to-noise ratios compared to the fluorinated diamagnetic reference.
APA:
Pujales Paradela, R. (2019). Reinforced Ni(ii)-cyclam derivatives as dual H-1/F-19 MRI probes. Chemical Communications, 55(28), 4115-4118. https://dx.doi.org/10.1039/c9cc01204d
MLA:
Pujales Paradela, Rosa. "Reinforced Ni(ii)-cyclam derivatives as dual H-1/F-19 MRI probes." Chemical Communications 55.28 (2019): 4115-4118.
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