Phantom Studies of Neutron Capture of Boron Containing Magnetic Nanoparticles
Tietze R, Dürr S, Lyer S, Taccardi N, Wasserscheid P, Canella L, Wagner FM, Petry W, Alexiou C (2013)
Publication Type: Journal article
Publication year: 2013
Journal
Abstract
The main burden that hinders the translation of neutron capture therapy drafts to human trials is the difficulty to deposit a sufficient amount of boron in the targeted tumour areas. Magnetic nanoparticles containing B-10 isotopes attempt to be enriched in tumour tissues selectively by the means of external magnetic fields to overcome these restrictions. First pilot measurements of the neutron depth penetration investigated the neutron flux density in dependence of depth, presence of boron and additional presence of iron oxide nanoparticles. These irradiation experiments on different phantoms evidenced no disturbing attenuation effects of the applied boron and the co-present nanoparticles in the samples.
Authors with CRIS profile
Rainer Tietze
Department of Otorhinolaryngology – Head and Neck Surgery (HNO-Klinik)
Stephan Dürr
Lehrstuhl für Hals-, Nasen- und Ohrenheilkunde
Stefan Lyer
Department of Otorhinolaryngology – Head and Neck Surgery (HNO-Klinik)
Nicola Taccardi
Lehrstuhl für Chemische Reaktionstechnik (CRT)
Peter Wasserscheid
Lehrstuhl für Chemische Reaktionstechnik (CRT)
Christoph Alexiou
Professur für Nanomedizin
Additional Organisation(s)
Involved external institutions
Germany (DE)How to cite
APA:
Tietze, R., Dürr, S., Lyer, S., Taccardi, N., Wasserscheid, P., Canella, L.,... Alexiou, C. (2013). Phantom Studies of Neutron Capture of Boron Containing Magnetic Nanoparticles. Biomedizinische Technik. https://doi.org/10.1515/bmt-2013-4045
MLA:
Tietze, Rainer, et al. "Phantom Studies of Neutron Capture of Boron Containing Magnetic Nanoparticles." Biomedizinische Technik (2013).
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