4-D motion animation of coronary arteries from rotational angiography

Holub W, Rohkohl C, Schuldhaus D, Prümmer M, Lauritsch G, Hornegger J (2011)

Publication Type: Conference contribution, Conference Contribution

Publication year: 2011


Original Authors: Holub W., Rohkohl C., Schuldhaus D., Prümmer M., Lauritsch G., Hornegger J.

Book Volume: 7964

Pages Range: -

Event location: Lake Buena Vista, FL

Journal Issue: null

DOI: 10.1117/12.877969


Time-resolved 3-D imaging of the heart is a major research topic in the medical imaging community. Recent advances in the interventional cardiac 3-D imaging from rotational angiography (C-arm CT) are now also making 4-D imaging feasible during procedures in the catheter laboratory. State-of-the-art reconstruction algorithms try to estimate the cardiac motion and utilize the motion field to enhance the reconstruction of a stable cardiac phase (diastole). The available data offers a handful of opportunities during interventional procedures, e.g. the ECG-synchronized dynamic roadmapping or the computation and analysis of functional parameters. In this paper we will demonstrate that the motion vector field (MVF) that is output by motion compensated image reconstruction algorithms is in general not directly usable for animation and motion analysis. Dependent on the algorithm different defects are investigated. A primary issue is that the MVF needs to be inverted, i.e. the wrong direction of motion is provided. A second major issue is the non-periodicity of cardiac motion. In algorithms which compute a non-periodic motion field from a single rotation the in depth motion information along viewing direction is missing, since this cannot be measured in the projections. As a result, while the MVF improves reconstruction quality, it is insufficient for motion animation and analysis. We propose an algorithm to solve both problems, i.e. inversion and missing in-depth information in a unified framework. A periodic version of the MVF is approximated. The task is formulated as a linear optimization problem where a parametric smooth motion model based on B-splines is estimated from the MVF. It is shown that the problem can be solved using a sparse QR factorization within a clinical feasible time of less than one minute. In a phantom experiment using the publicly available CAVAREV platform, the average quality of a non-periodic animation could be increased by 39% by applying the proposed periodization and inversion method. © 2011 SPIE.

Authors with CRIS profile

Involved external institutions

How to cite


Holub, W., Rohkohl, C., Schuldhaus, D., Prümmer, M., Lauritsch, G., & Hornegger, J. (2011). 4-D motion animation of coronary arteries from rotational angiography. In Proceedings of the Medical Imaging 2011: Visualization, Image-Guided Procedures, and Modeling (pp. -). Lake Buena Vista, FL.


Holub, Wolfgang, et al. "4-D motion animation of coronary arteries from rotational angiography." Proceedings of the Medical Imaging 2011: Visualization, Image-Guided Procedures, and Modeling, Lake Buena Vista, FL 2011. -.

BibTeX: Download