LE1-IZKF-J127: Exploiting mechanisms of ferroptosis sensitivity and resistance for novel cancer treatment options

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.09.2026

End date : 28.02.2029


Project details

Scientific Abstract

Integrating ferroptosis-inducing strategies into current standard-of care cancer therapies represents a promising approach to eliminate therapy-resistant, highly mesenchymal subpopulations. This project aims to identify effective combination treatments that target the heterogeneous tumor mass. Elucidating the molecular mechanisms underlying ferroptosis sensitivity and resistance will lead to a more precise and cancer-specific ferroptosis activation to improve therapeutic strategies.

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