D44: How Bacterial Nanoparticles Influence Tumor Initiation and Microenvironmental Remodeling
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.07.2026
End date : 31.12.2028
Project details
Scientific Abstract
The gut microbiota is a key contributor to colorectal cancer (CRC). Our data suggest that bacterial nanoparticles act as shuttles delivering microbial effectors to intestinal stem cells. We hypothesize that they promote CRC initiation and progression by transferring genotoxins and modulating the tumor microenvironment. This project aims to dissect how bacterial nanoparticles influence tumor cells and the TME.
