E39: The role of oligodendrocytes in prefrontal circuits: implications for schizophrenia pathogenesis and treatment
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.06.2026
End date : 30.11.2028
Project details
Scientific Abstract
This project investigates the role of oligodendroglia in schizophrenia, focusing on neural circuit dysfunction using a mouse model of psychosis. It assesses oligodendroglial function and prefrontal sphingolipid metabolism during psychosis induction and treatment, examines the impact of myelination on neural coding in cognitive circuits and studies the excitability of oligodendroglia in behaving mice. This research aims to advance understanding of schizophrenia pathogenesis and treatment.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Lehrstuhl für Biochemie und Pathobiochemie
