J115: Conjugated steroids in plasma and urine as diagnostic and prognostic biomarkers for adrenocortical carcinoma
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.08.2024
End date : 31.01.2027
Project details
Scientific Abstract
A rapid and unambiguous differential diagnosis of adrenal tumors is challenging, but of high clinical relevance. In a preliminary untargeted metabolomics study, conjugated steroids in urine were identified as potentially very promising diagnostic biomarkers. This project aims to develop a quantitative LC-MS assay for steroid conjugates in urine and plasma for a detailed investigation of their utility as diagnostic and prognostic biomarkers for adrenocortical carcinoma in a larger patient cohort.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Professur für Pharmazeutische Chemie
Lehrstuhl für Klinische Pharmakologie und Klinische Toxikologie
Medizinische Fakultät
