P049: Psoriatic arthritis: How inflammation spreads from the skin to the joint

FAU own research funding: EFI / IZKF / EAM ...


Start date : 16.10.2019

End date : 15.10.2020


Project details

Scientific Abstract

To date, it is still obscure why in some patients with psoriasis the autoimmune process is restrained to the skin, whereas in other it extends to the joints. We will take advantage of models resembling psoriatic arthritis, with the aim of studying the joint involvement secondary to skin inflammation. The understanding and characterization of the underlying mechanisms involved in the “skin-joint axis” is pivotal for a better comprehension of the link between physical barriers and autoimmunity

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