J106: Tissue imprinting of skin-derived immune cells in psoriatic arthritis

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.09.2023

End date : 28.02.2026


Project details

Scientific Abstract

To date, it is still obscure why in some patients with psoriasis the autoimmune process is restrained to the skin, whereas in other it extends to the joints. We will adopt models resembling psoriasis and psoriatic arthritis, with the aim of studying the joint involvement secondary to skin inflammation. The comprehension and characterization of the underlying mechanisms involved in the “skin-joint axis” is pivotal for a better understanding of the link between physical barriers and autoimmunity.

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