P134: Untargeted metabolomics in adrenal tumors: Screening for novel diagnostic biomarkers in urine
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.08.2023
End date : 31.07.2024
Project details
Scientific Abstract
The diagnostic workup of frequent adrenocortical adenomas and rare, aggressive adrenocortical carcinomas is challenging and lacks specificity. Determination of deconjugated steroids in urine is an emerging and promising tool in this field, however, the currently best available diagnostic biomarkers provide no benefit to a third of the patients. We plan to screen the urinary metabolome by untargeted metabolomics looking for more suitable diagnostic biomarkers such as intact steroid conjugates.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Lehrstuhl für Klinische Pharmakologie und Klinische Toxikologie
Medizinische Fakultät
