P129: Development of biofabricated 3D breast cancer in a perfusion reactor as tumor angiogenesis and therapy model
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.08.2023
End date : 31.07.2024
Project details
Scientific Abstract
Aim is the development of biofabricated 3D breast cancer models, which will act as standardized tumor angiogenesis and therapy models mimicking the in vivo situation by using multiple cell types including endothelial cells as well as the supply via a perfusion bioreactor. Evaluation will be based on metabolic activity, proteomic analysis, microscopy and histology. Assessment as therapeutic model will be done using paclitaxel. Goal is the use in basic research and the improvement of therapies.
Involved:
Contributing FAU Organisations:
Department of Plastic and Hand Surgery
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Medizinische Fakultät
