D040: The role of the DEAD-box RNA helicase DDX46 in liver cancer
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.03.2023
End date : 31.08.2025
Project details
Scientific Abstract
The neuropeptide Y (NPY) system was shown by the applicant to be a major driver of HCC. Transcriptome screening revealed that DEAD-box RNA helicase DDX46 is a novel and attractive NPY-regulated target in HCC. The major aims of this study are to characterize NPY-mediated regulation of DDX46 and to decipher the role of DDX46 as a novel and promising diagnostic and therapeutic target in HCC.
Involved:
Contributing FAU Organisations:
Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Medizinische Fakultät
