J099: The role of reactive carbonyls in metabolic-dysfunction associated neuropathic pain and chronic liver disease

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.10.2022

End date : 31.05.2025

Extension date: 30.09.2025


Project details

Scientific Abstract

Reactive carbonyl species (RCS) are linked to development of metabolic syndrome including neuropathic pain and steatotic liver disease (MASLD), but the possibly synergistic role of RCS in both conditions remains to be investigated. This project aims at analyzing RCS as biomarkers in patients with neuropathy and neuropathic pain, with parallel compre¬hensive experimental neurophysiological examinations of pa¬tients and assessment of functional effects of RCS on sensory neurons in vitro.

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