P108: Glomerular cell-derived exosome characterization and nanoparticles as therapeutic option in renal disease
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.05.2022
End date : 31.10.2022
Project details
Scientific Abstract
In this project we want to investigate cell-to-communication via exosomes and functionalized nanoparticles in the context of glomerular diseases. Therefore, we will characterize microvesicles secreted from glomerular cells regarding size and surface markers with electron and fluorescence microscopy and flow cytometry. Also, we want to study functionalized nanoparticles in vitro in glomerular cells and in vivo in a zebrafish model. Lastly, we want to establish an autophagy model in zebrafish.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 4 – Nephrology and Hypertension
Medizinische Fakultät
