J089: Multispectral optoacoustic tomography for non invasive characterization of strictures in Crohn’s disease

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.01.2021

End date : 30.06.2023

Extension date: 31.03.2024


Project details

Scientific Abstract

Intestinal strictures are a major disease burden in Crohn’s disease. Conventional cross-sectional imaging modalities are currently not able to differentiate between inflammatory and fibrotic components of strictures. This would be essential for the initiation of the appropriate therapy. In a translational approach we want to investigate whether optoacoustic imaging can be used to quantify hemoglobin as a sign of inflammation and collagen as a sign of fibrosis in murine and human intestine.

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