A082: Understanding the role of RANTES in the resolution of allergic asthma
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.02.2020
End date : 31.07.2022
Extension date: 31.01.2023
Project details
Scientific Abstract
We identified RANTES as a key regulator of the resolution of allergic asthma in human and murine studies. Resolved symptomatic episodes of asthma in children, were found to be associated with elevated serum levels of RANTES indicating the involvement of RANTES in the resolution of allergic asthma. In a murine model after allergen (HDM) challenge, RANTES cured allergic asthma trait. In this project, we want to better understand the mechanism of RANTES mediated resolution of allergic asthma.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Professur für Molekulare Pneumologie
Medizinische Fakultät
