P032: Multimodal longitudinal in vivo imaging of inflammation and bone remodeling in experimental enthesitis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.02.2020
End date : 16.09.2020
Project details
Scientific Abstract
Abnormal neo-ossification in humans with SpA and gout are common, but there are only few suitable animal models. Conventional methods require a high number of animals or can only insufficiently distinguish between inflammatory edematous swelling and/or increased bone thickness. The aim of this application is to establish a mouse model of gouty enthesitis in vivo by means of a non-invasive combination of MRI and PET/CT, in which live animals can longitudinally be examined.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 3 – Rheumatology and Immunology
Medizinische Fakultät
