FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.07.2020
End date : 31.12.2022
Extension date: 30.06.2023
Inflammation within the CNS can directly affect neuronal structures. Thus, molecules controlling inflammatory responses are of upmost importance. The immune-regulatory CD83 molecule is highly expressed by microglia and tissue-resident macrophages and thus, represents a crucial factor for microglial activation and the neuro-immune crosstalk. Since, its regulation and function in these cells has not been elucidated we will investigate this during immune homeostasis and neuroinflammation.