A089: CD83 as a key regulator during immune homeostasis and neuroinflammation

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.07.2020

End date : 31.12.2022

Extension date: 30.06.2023


Project details

Scientific Abstract

Inflammation within the CNS can directly affect neuronal structures. Thus, molecules controlling inflammatory responses are of upmost importance. The immune-regulatory CD83 molecule is highly expressed by microglia and tissue-resident macrophages and thus, represents a crucial factor for microglial activation and the neuro-immune crosstalk. Since, its regulation and function in these cells has not been elucidated we will investigate this during immune homeostasis and neuroinflammation.

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