Third Party Funds Group - Overall project
Acronym: ForInter
Start date : 01.03.2019
End date : 28.02.2023
Extension date: 31.12.2023
ForInter aims to analyse the cell-cell interaction of human neural cells. The studies will use from induced plurioptent stem cells (IPSCs) derived neurons, oligodendrocytes, astrocytes, microglia, pericytes.
The human brain has a complicated architecture of divers and specialised
cells, like neurons, glial and microglial cells. These cells form and
interact in functional and dynamic circuits, thus providing the basis
for the complex functions of the human brain.
Even though our
understanding of the human brain has made tremendous advances in recent
decades, many questions about the physiological and pathological
functions of the human brain remain unanswered until to date. The
structural analysis of the brain can be performed in post mortem brain
tissue, but these neuroanatomical and pathological studies only
represent a static approach and reflect the specific variables only at a
fixed point of time. For a deeper understanding, dynamic and functional
investigations of the interaction between the different cells in the
human brain are required.
Therefore, the Bavarian Consortium
ForInter aims to investigate the interaction between the different cell
types in the human brain using multidimensional cell culture systems.