Establishment of a heart support system as a contractile membrane based on the pericardium
Third party funded individual grant
Start date : 01.05.2016
End date : 31.03.2021
Extension date: 15.07.2022
Project details
Scientific Abstract
This project contains the establishment of a heart support system as a contractile membrane based on the pericardium to minimize the consequences of severe heart disease and to maintain proper cardiac function. The project is a research cooperation between the Institute of Applied Dynamics and the Pediatric Cardiology at the Friedrich-Alexander-Universität Erlangen-Nürnberg and is funded by the Klaus Tschira Foundation.
The project includes the study of cardiac function under pathological and normal conditions by developing computer models of the heart, which are validated with experimental data of pediatric cardiology of the University of Erlangen Nuremberg. The clinical measurements and experimental data, as well as the simulation model are based on rat hearts. Subsequently, a cardiac support system based on a membrane is to be designed to improve or at least maintain heart function under pathological conditions.
In particular at the Institute of Applied Dynamics, we are focusing on the development of the underlying computational heart model including the anatomy, morphology, electrophysiology and also the fluid-structure interaction to be able to build up the optimized heart support system but also to better understand the function of the heart and thus to predict or early detect cardiac dysfunctions and bring new treatments to the clinic.
Involved:
Sigrid Leyendecker
Project Leader
Minh Tuan Duong
Project Member
David Holz
Project Member
Denisa Martonová
Project Member
