Sewar Alkhashrom

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Professur für Pharmazeutische Chemie Lehrstuhl für Pharmazeutische Chemie
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A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex (2022) Alkhashrom S, Kicuntod J, Stillger K, Luetzenburg T, Anzenhofer C, Neundorf I, Marschall M, Eichler J Journal article The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity (2022) Schweininger J, Kriegel M, Häge S, Conrad M, Alkhashrom S, Lösing J, Weiler S, et al. Journal article A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro (2022) Aillaud I, Kaniyappan S, Chandupatla RR, Ramirez LM, Alkhashrom S, Eichler J, Horn A, et al. Journal article A PROSS-designed extensively mutated estrogen receptor α variant displays enhanced thermal stability while retaining native allosteric regulation and structure (2021) Kriegel M, Wiederanders HJ, Alkhashrom S, Eichler J, Muller Y Journal article Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors (2021) Alkhashrom S, Kicuntod J, Häge S, Schweininger J, Muller Y, Lischka P, Marschall M, Eichler J Journal article Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule (2021) Kicuntod J, Alkhashrom S, Häge S, Diewald B, Müller R, Hahn F, Lischka P, et al. Journal article Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties (2020) Marschall M, Häge S, Conrad M, Alkhashrom S, Kicuntod J, Schweininger J, Kriegel M, et al. Journal article, Review article High-resolution crystal structures of two prototypical β- And γ-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity (2020) Muller Y, Häge S, Alkhashrom S, Höllriegl T, Weigert S, Dolles S, Hof K, et al. Journal article