PD Dr. Alexandr Ilyaskin

Medizinische Fakultät Lehrstuhl für Physiologie (Vegetative Physiologie)

Ion channel function of polycystin-2/polycystin-1 heteromer revealed by structure-guided mutagenesis (2025) Staudner T, Khamseekaew J, Madej MG, Geiges L, Azemi B, Ziegler C, Korbmacher C, Ilyaskin A Journal article Disease-associated missense mutations in the pore loop of polycystin-2 alter its ion channel function in a heterologous expression system (2024) Staudner T, Geiges L, Khamseekaew J, Sure F, Korbmacher C, Ilyaskin A Journal article The small molecule activator S3969 stimulates the epithelial sodium channel by interacting with a specific binding pocket in the channel's β-subunit (2024) Sure F, Einsiedel J, Gmeiner P, Duchstein P, Zahn D, Korbmacher C, Ilyaskin A Journal article Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney (2024) Sure F, Afonso S, Essigke D, Schmidt P, Kalo MZ, Nesterov V, Kißler A, et al. Journal article Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit (2022) Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej MG, Wittmann S, et al. Conference contribution Transmembrane serine protease 2 (TMPRSS2) is involved in proteolytic activation of the epithelial sodium channel (ENaC) in mouse cortical collecting duct (mCCDcl1) cells (2022) Sure F, Afonso S, Bertog M, Rinke R, Wittmann S, Gramberg T, Ilyaskin A, Korbmacher C Conference contribution Early effects of aldosterone on Na+ transport and the transcriptome of cultured mouse cortical collecting duct cells (mCCDcl1) (2022) Afonso S, Bertog M, Ilyaskin A, Büttner C, Ekici AB, Korbmacher C Conference contribution Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit (2022) Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej MG, Wittmann S, et al. Journal article Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels (2022) Keely SJ, Urso A, Ilyaskin A, Korbmacher C, Bunnett NW, Poole DP, Carbone SE Journal article, Review article Epithelialer Natriumkanal (ENaC) im distalen Nephron: Zentrale Rolle von ENaC für die Na+- und K+-Homöostase (2022) Ilyaskin A, Korbmacher C Journal article