Dr. Astrid Schweizer

Targeting Human CD22/Siglec-2 with Dimeric Sialosides as Novel Oligosaccharide Mimetics (2022) Prescher H, Schweizer A, Frank M, Kuhfeldt E, Ring J, Nitschke L Journal article The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45-/- immunodeficient B cells (2022) Akatsu C, Alborzian Deh Sheikh A, Matsubara N, Takematsu H, Schweizer A, Abdu-Allah HH, Tedder TF, et al. Journal article New Human CD22/Siglec-2 Ligands with a Triazole Glycoside. (2017) Prescher H, Schweizer A, Kuhfeldt E, Nitschke L, Brossmer R Journal article Design, Synthesis, and Biological Evaluation of Small, High-Affinity Siglec-7 Ligands: Toward Novel Inhibitors of Cancer Immune Evasion (2017) Prescher H, Frank M, Guetgemann S, Kuhfeldt E, Schweizer A, Nitschke L, Watzl C, Brossmer R Journal article Discovery of Multifold Modified Sialosides as Human CD22/Siglec-2 Ligands with Nanomolar Activity on B-Cells (2014) Prescher H, Schweizer A, Kuhfeldt E, Nitschke L, Brossmer R Journal article, Original article Gene Trap Mice Reveal an Essential Function of Dual Specificity Phosphatase Dusp16/MKP-7 in Perinatal Survival and Regulation of Toll-like Receptor (TLR)-induced Cytokine Production (2014) Niedzielska M, Bodendorfer B, Muench S, Eichner A, Derigs M, Da Costa O, Schweizer A, et al. Journal article Targeting of CD22-positive B-cell lymphoma cells by synthetic divalent sialic acid analogues (2012) Schweizer A, Wöhner M, Prescher H, Brossmer R, Nitschke L Journal article A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing (2011) Brenner S, Drewel D, Steinbart T, Weisel F, Härtel E, Pötzsch S, Welzel H, et al. Journal article NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network (2011) Bhattacharyya S, Deb J, Patra AK, Duong Anh Thuy Pham , Chen W, Vaeth M, Berberich-Siebelt F, et al. Journal article Swiprosin-1/EFhd2 Controls B Cell Receptor Signaling through the Assembly of the B Cell Receptor, Syk, and Phospholipase C gamma 2 in Membrane Rafts (2010) Kroczek C, Lang C, Brachs S, Grohmann M, Duetting S, Schweizer A, Nitschke L, et al. Journal article