BRIDGE Consortium e.V. (Bladder Cancer Research Initiative for Drug Targets Germany)

NECTIN4 Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer (2024) Klümper N, Tran NK, Zschäbitz S, Hahn O, Büttner T, Roghmann F, Bolenz C, et al. Journal article Membranous NECTIN-4 Expression Frequently Decreases during Metastatic Spread of Urothelial Carcinoma and Is Associated with Enfortumab Vedotin Resistance (2023) Klümper N, Ralser DJ, Ellinger J, Roghmann F, Albrecht J, Below E, Alajati A, et al. Journal article Reply to Jon Griffin. TIME for a Change? Multimarker Assessment of the Tumour Immune Microenvironment and Metastatic Site Biopsy to Improve Immunotherapy Response Prediction in Muscle-invasive Bladder Cancer. Eur Urol. 2023;43:143–4 (2023) Klümper N, Hölzel M, Eckstein M Journal article Reply to Mattias Höglund's Letter to the Editor re: Alexander Cox, Niklas Klümper, Johannes Stein, et al. Molecular Urothelial Tumor Cell Subtypes Remain Stable During Metastatic Evolution. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.03.020 (2023) Klümper N, Cox A, Eckstein M Journal article Re: First-in-Human Study of the Radioligand 68Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma: Navigating Metastatic Urothelial Cancer with Nectin-4 PET/CT (2023) Klümper N, Eckstein M, Hölzel M, Herrmann K, Hadaschik B, Grünwald V Journal article Molecular Urothelial Tumor Cell Subtypes Remain Stable During Metastatic Evolution (2023) Cox A, Klümper N, Stein J, Sikic D, Breyer J, Bolenz C, Roghmann F, et al. Journal article A genome-wide association study with tissue transcriptomics identifies genetic drivers for classic bladder exstrophy (2022) Mingardo E, Beaman G, Grote P, Nordenskjöld A, Newman W, Woolf AS, Eckstein M, et al. Journal article Spatial Immunephenotypes of Distant Metastases but not Matched Primary Urothelial Carcinomas Predict Response to Immune Checkpoint Inhibition (2022) Erlmeier F, Klümper N, Landgraf L, Strissel P, Strick R, Sikic D, Taubert H, et al. Journal article Integration of spatial pd-l1 expression with the tumor immune microenvironment outperforms standard pd-l1 scoring in outcome prediction of urothelial cancer patients (2021) Weyerer V, Strissel P, Strick R, Sikic D, Geppert CI, Bertz S, Lange F, et al. Journal article, Original article Utility of stromal tumor infiltrating lymphocyte scoring (sTILs) for risk stratification of patients with muscle-invasive urothelial bladder cancer after radical cystectomy (2021) Sikic D, Weyerer V, Geppert CI, Bertz S, Lange F, Taubert H, Wach S, et al. Journal article