Deutsches Primatenzentrum (DPZ), Leibniz-Institut für Primatenforschung

Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D (2025) Arora P, Zhang L, Nehlmeier I, Kempf A, Graichen L, Kreitz E, Sidarovich A, et al. Journal article Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies (2025) Mazigi O, Langley DB, Henry JY, Burnett DL, Sobti M, Walker GJ, Rouet R, et al. Journal article Mechanisms of sterilizing immunity provided by an HIV-1 neutralizing antibody against mucosal infection (2024) Richel E, Cordsmeier A, Bauer L, Fraedrich K, Vestweber R, Roshani B, Stolte-Leeb N, et al. Journal article ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization (2024) Zhang L, Cheng HH, Krüger N, Hörnich B, Graichen L, Hahn AS, Schulz S, et al. Journal article Comparative Analysis of Host Cell Entry Efficiency and Neutralization Sensitivity of Emerging SARS-CoV-2 Lineages KP.2, KP.2.3, KP.3, and LB.1 (2024) Chen N, Decker KE, Schulz S, Kempf A, Nehlmeier I, Moldenhauer AS, Dopfer-Jablonka A, et al. Journal article Genetic barrier to resistance: a critical parameter for efficacy of neutralizing monoclonal antibodies against SARS-CoV-2 in a nonhuman primate model (2024) Stahl-Hennig C, Peter AS, Cordsmeier A, Stolte-Leeb N, Vestweber R, Socher E, Merida SA, et al. Journal article Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage (2024) Zhang L, Dopfer-Jablonka A, Nehlmeier I, Kempf A, Graichen L, Calderón Hampel N, Cossmann A, et al. Journal article SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency (2024) Zhang L, Kempf A, Nehlmeier I, Cossmann A, Richter A, Bdeir N, Graichen L, et al. Journal article HIV-1 neutralizing antibodies provide sterilizing immunity by blocking infection of the first cells (2023) Stab V, Stahl-Hennig C, Enßer A, Richel E, Fraedrich K, Sauermann U, Tippler B, et al. Journal article Kaposi’s sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes (2023) Liu S, Großkopf AK, Yang X, Mannheim ME, Backovic M, Scribano S, Schlagowski S, et al. Journal article