Polymer-derived Biosilicate-C composite foams: In-vitro bioactivity, biocompatibility and antibacterial activity

Dogrul F, Nawaz Q, Elsayed H, Liverani L, Galusek D, Bernardo E, Boccaccini AR (2024)

Publication Type: Journal article

Publication year: 2024

Journal

Journal of the European Ceramic Society Elsevier

DOI: 10.1016/j.jeurceramsoc.2024.03.006

Abstract

Biosilicate/carbon composites were fabricated in the form of highly porous foams by the polymer-derived ceramic route, and their biological response was analysed. Two different commercial silicone polymers (a poly-methyl-siloxane, MK, and a polymethyl-phenyl-silsesquioxane, H44) were considered as a silica source, mixed with active fillers yielding Na2O, CaO and P2O5. The samples were heat treated either in air or in N2 atmosphere to obtain products resembling the known Biosilicate® glass-ceramic, with or without free carbon. All fabricated samples exhibited acellular in-vitro bioactivity upon immersion in SBF as well as antibacterial activity against S. aureus and E. coli. Direct contact cell viability test, assessed by using a WST-8 assay, indicated that both carbon-containing and carbon-free samples were cytocompatible.

Authors with CRIS profile

Qaisar Nawaz Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Liliana Liverani Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Trenčianska univerzita Alexandra Dubčeka v Trenčíne SK Slovakia (SK) University of Padua / Universita degli Studi di Padova IT Italy (IT)

How to cite

APA:

Dogrul, F., Nawaz, Q., Elsayed, H., Liverani, L., Galusek, D., Bernardo, E., & Boccaccini, A.R. (2024). Polymer-derived Biosilicate-C composite foams: In-vitro bioactivity, biocompatibility and antibacterial activity. Journal of the European Ceramic Society. https://doi.org/10.1016/j.jeurceramsoc.2024.03.006

MLA:

Dogrul, Fulden, et al. "Polymer-derived Biosilicate-C composite foams: In-vitro bioactivity, biocompatibility and antibacterial activity." Journal of the European Ceramic Society (2024).

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