Poly(ε-caprolactone)/bioactive glass composite electrospun fibers for tissue engineering applications
Piatti E, Miola M, Liverani L, Verné E, Boccaccini AR (2023)
Publication Type: Journal article
Publication year: 2023
Journal
DOI: 10.1002/jbm.a.37578
Abstract
In this work, composite electrospun fibers containing innovative bioactive glass nanoparticles were produced and characterized. Poly(ε-caprolactone), benign solvents, and sol–gel B- and Cu-doped bioactive glass powders were used to fabricate fibrous scaffolds. The retention of bioactive glass nanoparticles in the polymer matrix, the electrospinnability of this novel solution and the obtained electrospun composites were extensively characterized. As a result, composite electrospun fibers characterized by biocompatibility, bioactivity, and exhibiting overall properties adequate for both hard and soft tissue engineering applications, have been produced. The addition of these bioactive glass nanoparticles was, indeed, able to impart bioactive properties to the fibers. Cell culture studies show promising results, demonstrating proliferation and growth of cells on the composite fibers. Wettability, degradation rate, and mechanical performance were also tested and are in line with previous results.
Authors with CRIS profile
Liliana Liverani
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Aldo Boccaccini
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Involved external institutions
Italy (IT)How to cite
APA:
Piatti, E., Miola, M., Liverani, L., Verné, E., & Boccaccini, A.R. (2023). Poly(ε-caprolactone)/bioactive glass composite electrospun fibers for tissue engineering applications. Journal of Biomedical Materials Research Part A. https://dx.doi.org/10.1002/jbm.a.37578
MLA:
Piatti, Elisa, et al. "Poly(ε-caprolactone)/bioactive glass composite electrospun fibers for tissue engineering applications." Journal of Biomedical Materials Research Part A (2023).
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