Blood flow quantification using optical flow methods in a body fitted coordinate system

Maday P, Brosig R, Endres J, Kowarschik M, Navab N (2014)


Publication Type: Conference contribution

Publication year: 2014

Journal

Publisher: SPIE

Book Volume: 9034

Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Event location: USA

ISBN: 9780819498274

DOI: 10.1117/12.2043408

Abstract

In this paper a blood flow quantification method that is based on a physically motivated dense 2D flow estimation algorithm is outlined. It yields accurate time varying volumetric flow rate measurements based on digital subtraction angiography (DSA) image sequences, with robustness to significant inter-frame displacements. Time varying volumetric flow rates are estimated for individual non-branching vascular segments based on the estimated 2D flow fields and a 3D vessel segmentation from a 3D Rotational Angiography (3DRA) acquisition. The novelty of the approach lies in the use of a vessel aligned coordinate system for the problem formulation. The coordinate functions are generated using the Schwarz-Christoffel1(SC) map that yields a solution with coordinate lines aligned with the vessel boundaries. The use of vessel aligned coordinates enables the easy and accurate handling of boundary conditions in the irregular domain of a vessel lumen while only requiring slight modifications to the used finite difference approach. Unlike traditional coarse to fine methods we use an anisotropic scaling strategy that enables the estimation of flows with larger inter frame displacements. The evaluation of our method is based on highly realistic synthetic DSA datasets for a number of cases. Ground truth volumetric flow rate values are compared against the measurements and a high degree of fidelity is observed. Performance measures are obtained with varying flow velocities and acquisition rates. © 2014 SPIE.

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How to cite

APA:

Maday, P., Brosig, R., Endres, J., Kowarschik, M., & Navab, N. (2014). Blood flow quantification using optical flow methods in a body fitted coordinate system. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. USA: SPIE.

MLA:

Maday, Peter, et al. "Blood flow quantification using optical flow methods in a body fitted coordinate system." Proceedings of the Medical Imaging 2014: Image Processing, USA SPIE, 2014.

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