The two-minute walk test in persons with multiple sclerosis: Correlations of cadence with free-living walking do not support ecological validity

Karle V, Hartung V, Ivanovska K, Mäurer M, Flachenecker P, Pfeifer K, Tallner A (2020)

Publication Type: Journal article

Publication year: 2020

Journal

International Journal of Environmental Research and Public Health Multidisciplinary Digital Publishing Institute (MDPI)

Book Volume: 17

Pages Range: 1-11

Article Number: 9044

Journal Issue: 23

DOI: 10.3390/ijerph17239044

Abstract

The two-minute walk test (2MWT) is a frequently used walking capacity test in persons with multiple sclerosis (pwMS). However, less is known about its relevance with regards to walking capacity during free-living walking performance. Therefore, the ecological validity of the 2MWT was tested by 1. computing free-living minutes with the same intensity (cadence) as during the 2MWT and 2. investigating the relationship between 2MWT cadence and minutes with the same cadence during free-living walking. 20 pwMS aged 44.2 ± 12.2 (Expanded Disability Status Scale (EDSS) score of 3.1 ± 1.4) performed a 2MWT and wore an accelerometer for seven days. The number of pwMS reaching 100%, 90%, 80% or 70% of 2MWT cadence for at least one minute a day and minutes/day with at least 100%, 90%, 80% and 70% of 2MWT cadence during free-living walking was calculated. Six participants reached 100% of the 2MWT cadence for at least one minute/day during free-living walking. A total of 80% 2MWT cadence was the first intensity category that was reached by all participants during free-living walking. No significant correlation was found between cadence in the 2MWT and minutes in which this cadence was reached during free-living walking. Ecological validity with regard to walking intensity could not be confirmed in our study sample.

Authors with CRIS profile

Verena Hartung Lehrstuhl für Sportwissenschaft mit dem Schwerpunkt Bewegung und Gesundheit Klaus Pfeifer Lehrstuhl für Sportwissenschaft mit dem Schwerpunkt Bewegung und Gesundheit Alexander Tallner Lehrstuhl für Sportwissenschaft mit dem Schwerpunkt Bewegung und Gesundheit

Involved external institutions

Fraunhofer-Institut für Biomedizinische Technik (IBMT) / Fraunhofer Institute for Biomedical Engineering DE Germany (DE) Klinikum Würzburg Mitte DE Germany (DE)

How to cite

APA:

Karle, V., Hartung, V., Ivanovska, K., Mäurer, M., Flachenecker, P., Pfeifer, K., & Tallner, A. (2020). The two-minute walk test in persons with multiple sclerosis: Correlations of cadence with free-living walking do not support ecological validity. International Journal of Environmental Research and Public Health, 17(23), 1-11. https://dx.doi.org/10.3390/ijerph17239044

MLA:

Karle, Viktoria, et al. "The two-minute walk test in persons with multiple sclerosis: Correlations of cadence with free-living walking do not support ecological validity." International Journal of Environmental Research and Public Health 17.23 (2020): 1-11.

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