Effective SLOPE: EffectS of Lifestyle interventions in Older PEople with obesity: A systematic review and network meta-analysis protocol

Torbahn G, Schöne D, Schwingshackl L, Rücker G, Knüttel H, Kemmler W, Sieber C, Batsis JA, Villareal DT, Stroebele-Benschop N, Volkert D, Kießwetter E (2020)

Publication Type: Journal article

Publication year: 2020

Journal

BMJ Open BMJ Publishing Group

Book Volume: 10

Article Number: e038330

Journal Issue: 10

DOI: 10.1136/bmjopen-2020-038330

Abstract

Introduction Obesity is highly prevalent in older adults aged 65 years or older. Different lifestyle interventions (diet, exercise, self-management) are available but benefits and harms have not been fully quantified comparing all available health promotion interventions. Special consideration must be given to functional outcomes and possible adverse effects (loss of muscle and bone mass, hypoglycaemia) of weight loss interventions in this age group. The objective of this study is to synthesise the evidence regarding the effects of different types and modalities of lifestyle interventions, or their combinations, on physical function and obesity-related outcomes such as body composition in older adults with obesity. Methods and analyses Six databases (Medline, Embase, Cochrane Central Register of Controlled Trials, Cumulated Index to Nursing and Allied Health Literature (CINAHL), Psychinfo and Web of Science) and two trial registries (Clinicaltrials.gov and the WHO International Clinical Trials Registry Platform) will be searched for randomised controlled trials of lifestyle interventions in older adults with obesity. Screening (title/abstract and full-text) and data extraction of references as well as assessment of risk of bias and rating of the certainty of evidence (Grading of Recommendations, Assessment, Development and Evaluation for network meta-analyses) will be performed by two reviewers independently. Frequentist random-effects network meta-analyses will be conducted to determine the pooled effects from each intervention. Ethics and dissemination We will submit our findings to peer-reviewed journals and present at national and international conferences as well as in scientific medical societies. Patient-targeted dissemination will involve local and national advocate groups. PROSPERO registration number CRD42019147286.

Authors with CRIS profile

Gabriel Torbahn Lehrstuhl für Innere Medizin (Geriatrie) Daniel Schöne Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Wolfgang Kemmler Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Cornel Sieber Lehrstuhl für Innere Medizin (Geriatrie) Dorothee Volkert Professur für Klinische Ernährung im Alter Eva Kießwetter Professur für Klinische Ernährung im Alter

Involved external institutions

Albert-Ludwigs-Universität Freiburg DE Germany (DE) Universität Regensburg DE Germany (DE) University of North Carolina at Chapel Hill US United States (USA) (US) Baylor College of Medicine US United States (USA) (US) Universität Hohenheim DE Germany (DE)

How to cite

APA:

Torbahn, G., Schöne, D., Schwingshackl, L., Rücker, G., Knüttel, H., Kemmler, W.,... Kießwetter, E. (2020). Effective SLOPE: EffectS of Lifestyle interventions in Older PEople with obesity: A systematic review and network meta-analysis protocol. BMJ Open, 10(10). https://dx.doi.org/10.1136/bmjopen-2020-038330

MLA:

Torbahn, Gabriel, et al. "Effective SLOPE: EffectS of Lifestyle interventions in Older PEople with obesity: A systematic review and network meta-analysis protocol." BMJ Open 10.10 (2020).

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