Quantitative Imaging of the Iron-Oxide Nanoparticle- Concentration for Magnetic Drug Targeting Employing Inverse Magnetomotive Ultrasound

Fink M, Lyer S, Alexiou C, Rupitsch S, Ermert H (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Current Directions in Biomedical Engineering De Gruyter

Book Volume: 5

Pages Range: 417-419

Journal Issue: 1

DOI: 10.1515/cdbme-2019-0105

Abstract

Magnetomotive Ultrasound is an imaging technique that is capable to detect tissue, which is perfused by magnetic nanoparticles. However, this modality is restricted to qualitative imaging only. Therefore, we present an extended Magnetomotive Ultrasound algorithm, which allows the quantitative determination of the spatial distribution of magnetic nanoparticle density in tissue. The algorithm is based on an iterative adjustment of simulated data to measurements. Experiments with tissue-mimicking phantoms reveal that the presented method leads to the spatial particle concentration in the correct order of magnitude.

Authors with CRIS profile

Michael Fink Lehrstuhl für Autonome Systeme und Mechatronik Stefan Lyer Department of Otorhinolaryngology – Head and Neck Surgery Christoph Alexiou Professur für Nanomedizin Stefan Rupitsch Lehrstuhl für Autonome Systeme und Mechatronik Helmut Ermert Lehrstuhl für Autonome Systeme und Mechatronik

How to cite

APA:

Fink, M., Lyer, S., Alexiou, C., Rupitsch, S., & Ermert, H. (2019). Quantitative Imaging of the Iron-Oxide Nanoparticle- Concentration for Magnetic Drug Targeting Employing Inverse Magnetomotive Ultrasound. Current Directions in Biomedical Engineering, 5(1), 417-419. https://dx.doi.org/10.1515/cdbme-2019-0105

MLA:

Fink, Michael, et al. "Quantitative Imaging of the Iron-Oxide Nanoparticle- Concentration for Magnetic Drug Targeting Employing Inverse Magnetomotive Ultrasound." Current Directions in Biomedical Engineering 5.1 (2019): 417-419.

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