Psychosocial outcome in epilepsy after extratemporal surgery

Journal article


Publication Details

Author(s): Walther K, Onugoren MD, Buchfelder M, Gollwitzer S, Graf W, Kasper B, Kriwy P, Kurzbuch K, Lang J, Roessler K, Schwab S, Schwarz M, Stefan H, Hamer H
Journal: Epilepsy and Behavior
Publication year: 2018
Volume: 81
Pages range: 94-100
ISSN: 1525-5050


Abstract

OBJECTIVE: Only limited data exist on psychosocial long-term outcome after epilepsy surgery in patients with extratemporal epilepsy. The aim of this study was to investigate psychosocial outcome after extratemporal epilepsy surgery and to assess factors predicting favorable outcome.
METHOD: Sixty-five out of 104 eligible patients who had undergone extratemporal epilepsy surgery at our epilepsy center between 1990 and 2015 (mean age: 42.2. years; 75% of the resections in the frontal lobe) completed a questionnaire asking about seizure status, employment status, marital and living situation, driving status, depressive symptoms, and quality of life (QOL). Follow-up was on average 9.2years after surgery (range: 1-26years).
RESULTS: Thirty-eight (58%) patients were free of disabling seizures (Engel class I), and 28 (43%) have not experienced any seizures after surgery (Engel class IA). Employment rate in the primary labor market remained at 45%, but more patients lost employment (14%) than gained employment (8%). Postoperative employment was predicted by preoperative employment (p=.007), seizure freedom (p=.025), older age at seizure onset (p=.018), younger age at follow-up (p=.035), and female gender (p=.048). Seizure-free patients were more likely to be driving; have a partner, particularly in males; and have lower depressive scores. Quality of life at follow-up was best predicted by employment (p=.012), partnership (p=.025), and seizure freedom (p=.025). In contrast, recurrence of seizures and early seizure onset were associated with poor psychosocial outcome, particularly in men.
CONCLUSION: The study provides support that extratemporal surgery can lead to improved QOL and favorable psychosocial outcome. Seizure freedom is important but not the only determinant of good psychosocial outcome.


FAU Authors / FAU Editors

Buchfelder, Michael Prof. Dr.
Lehrstuhl für Neurochirurgie
Hamer, Hajo Prof. Dr. med.
Professur für Epileptologie
Kasper, Burkhard Prof. Dr.
Medizinische Fakultät
Kurzbuch, Katrin
Medizinische Fakultät
Schwab, Stefan Prof. Dr.
Lehrstuhl für Neurologie
Schwarz, Michael Dr. rer. biol. hum.
Neurologische Klinik
Stefan, Hermann Prof. Dr.
Medizinische Fakultät


External institutions with authors

Technische Universität Chemnitz


How to cite

APA:
Walther, K., Onugoren, M.D., Buchfelder, M., Gollwitzer, S., Graf, W., Kasper, B.,... Hamer, H. (2018). Psychosocial outcome in epilepsy after extratemporal surgery. Epilepsy and Behavior, 81, 94-100. https://dx.doi.org/10.1016/j.yebeh.2018.01.038

MLA:
Walther, Katrin, et al. "Psychosocial outcome in epilepsy after extratemporal surgery." Epilepsy and Behavior 81 (2018): 94-100.

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Last updated on 2019-28-02 at 22:10