Endoscopic Laser-Based 3D Imaging for Functional Voice Diagnostics

Journal article

Publication Details

Author(s): Semmler M, Kniesburges S, Parchent J, Jakubass B, Zimmermann M, Bohr C, Schützenberger A, Döllinger M
Journal: Applied Sciences
Publication year: 2017
Volume: 7
Journal issue: 6
ISSN: 2076-3417


Recently, we reported on the in vivo application of a miniaturized measuring device for 3D visualization of the superior vocal fold vibrations from high-speed recordings in combination with a laser projection unit (LPU). As a long-term vision for this proof of principle, we strive to integrate the further developed laserendoscopy as a diagnostic method in daily clinical routine. The new LPU mainly comprises a Nd:YAG laser source (532nm/CW/2 omega) and a diffractive optical element (DOE) generating a regular laser grid (31 x 31 laser points) that is projected on the vocal folds. By means of stereo triangulation, the 3D coordinates of the laser points are reconstructed from the endoscopic high-speed footage. The new design of the laserendoscope constitutes a compromise between robust image processing and laser safety regulations. The algorithms for calibration and analysis are now optimized with respect to their overall duration and the number of required interactions, which is objectively assessed using binary classifiers. The sensitivity and specificity of the calibration procedure are increased by 40.1% and 22.3%, which is statistically significant. The overall duration for the laser point detection is reduced by 41.9%. The suggested semi-automatic reconstruction software represents an important stepping-stone towards potential real time processing and a comprehensive, objective diagnostic tool of evidence-based medicine.

FAU Authors / FAU Editors

Bohr, Christopher PD Dr.
Professur für Laryngologie
Döllinger, Michael Prof. Dr.
Professur für Computational Medicine (DFG-Forschungsprofessur)
Kniesburges, Stefan PD Dr.-Ing.
Phoniatrische und Pädaudiologische Abteilung in der Hals-Nasen-Ohren-Klinik
Schützenberger, Anne Dr. med.
Hals-Nasen-Ohren-Klinik - Kopf- und Halschirurgie
Semmler, Marion Dr.-Ing.
Phoniatrische und Pädaudiologische Abteilung in der Hals-Nasen-Ohren-Klinik

External institutions with authors

Bayerisches Laserzentrum gemeinnützige Forschungsgesellschaft mbH (BLZ)

How to cite

Semmler, M., Kniesburges, S., Parchent, J., Jakubass, B., Zimmermann, M., Bohr, C.,... Döllinger, M. (2017). Endoscopic Laser-Based 3D Imaging for Functional Voice Diagnostics. Applied Sciences, 7(6).

Semmler, Marion, et al. "Endoscopic Laser-Based 3D Imaging for Functional Voice Diagnostics." Applied Sciences 7.6 (2017).


Last updated on 2019-19-06 at 08:17