Universidade Federal de Minas Gerais (UFMG)


University / College

Location:
Belo Horizonte, Brazil


Research projects with FAU researchers


(The genus Digitalis: Molecular taxonomy, preservation, active constituents and therapeutic applications):
DIGITALIS: The genus Digitalis: Molecular taxonomy, preservation, active constituents and therapeutic applications
Prof. Dr. Wolfgang Kreis
(01/05/2012 - 30/04/2016)


Publications in cooperation with FAU scientists


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Boff, L., Munkert, J., Ottoni, F.M., Schneider, N.F.Z., Ramos, G.S., Kreis, W.,... Simões, C.M.O. (2019). Potential anti-herpes and cytotoxic action of novel semisynthetic digitoxigenin-derivatives. European Journal of Medicinal Chemistry, 167, 546-561. https://dx.doi.org/10.1016/j.ejmech.2019.01.076
Schneider, N.F.Z., Cerella, C., Lee, J.-Y., Mazumder, A., Kim, K.R., de Carvalho, A.,... Diederich, M. (2018). Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-specific Cell Death. Frontiers in Pharmacology, 9. https://dx.doi.org/10.3389/fphar.2018.00070
Silva, I.T., Munkert, J., Nolte, E., Schneider, N.F.Z., Rocha, S.C., Ramos, A.C.P.,... Simões, C.M.O. (2018). Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+ -ATPase inhibition. Biomedicine & Pharmacotherapy, 107, 464-474. https://dx.doi.org/10.1016/j.biopha.2018.08.028
Gomes, E.R., Novais, M.V.M., Silva, I.T., Barros, A.L.B., Leite, E.A., Munkert, J.,... Oliveira, M.C. (2018). Long-circulating and fusogenic liposomes loaded with a glucoevatromomoside derivative induce potent antitumor response. Biomedicine & Pharmacotherapy, 108, 1152 - 1161. https://dx.doi.org/10.1016/j.biopha.2018.09.109
Peixoto-Santos, J.E., Drumond De Carvalho, L.E., Kandratavicius, L., Beserra Diniz, P.R., Scandiuzzi, R.C., Coras, R.,... Leite, J.P. (2018). Manual Hippocampal Subfield Segmentation Using High-Field MRI: Impact of Different Subfields in Hippocampal Volume Loss of Temporal Lobe Epilepsy Patients. Frontiers in Neurology, 9. https://dx.doi.org/10.3389/fneur.2018.00927
Nolte, E., Wach, S., Silva, I.T., Lukat, S., Ekici, A.B., Munkert, J.,... Lai, X. (2017). A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines. Oncotarget. https://dx.doi.org/10.18632/oncotarget.14644
Kreis, W., Munkert, J., & De Padua, R.M. (2017). Biossíntese de metabólitos primários e secundários. In Letícia Bispo de Lima (Eds.), Farmacognosia do Produto Natural ao Medicamento. (pp. 147 - 166). Porto Alegre, Brazil: Artmed Editora Ltda..
Schneider, N.F.Z., Persich, L., Rocha, S.C., Ramos, A.C.P., Cortes, V.F., Silva, I.T.,... Simões, C.M.O. (2017). Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase. Biomedicine & Pharmacotherapy, 97, 684-696. https://dx.doi.org/10.1016/j.biopha.2017.10.128
Schneider, N.F.Z., Silva, I.T., Persich, L., de Carvalho, A., Rocha, S.C., Marostica, L.L.,... Simões, C.M.O. (2017). Cytotoxic effects of the cardenolide convallatoxin and its Na,K-ATPase regulation. Molecular and Cellular Biochemistry, 428(1), 23-39. https://dx.doi.org/10.1007/s11010-016-2914-8
Cederholm, T., Barazzoni, R., Austin, P., Ballmer, P., Biolo, G., Bischoff, S.C.,... Singer, P. (2017). ESPEN guidelines on definitions and terminology of clinical nutrition. Clinical Nutrition, 36(1), 49-64. https://dx.doi.org/10.1016/j.clnu.2016.09.004
Munkert, J., Santiago Franco, M., Nolte, E., Silva, I.T., Oliveira Castilho, R., Ottoni, F.M.,... De Padua, R.M. (2017). Production of the Cytotoxic Cardenolide Glucoevatromonoside by Semisynthesis and Biotransformation of Evatromonoside by a Digitalis lanata Cell Culture. Planta medica. https://dx.doi.org/10.1055/s-0043-109557
Domenig, O., Manzel, A., Grobe, N., Koenigshausen, E., Kaltenecker, C.C., Kovarik, J.J.,... Poglitsch, M. (2016). Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney. Scientific Reports, 6, 33678. https://dx.doi.org/10.1038/srep33678
Meitinger, N., Munkert, J., Maia de Pádua, R., De Souza Filho, J.D., Maid, H., Bauer, W.,... Kreis, W. (2016). The catalytic mechanism of the 3-ketosteroid isomerase of Digitalis lanata involves an intramolecular proton transfer and the activity is not associated with the 3 beta-hydroxysteroid dehydrogenase activity. Tetrahedron Letters, 57(14), 1567-1571. https://dx.doi.org/10.1016/j.tetlet.2016.02.099
Sanches dos Santos, L., Azevedo Antunes de Oliveira, C., dos Santos, C.S., Pereira, J.A., Sabbadini, P.S., das Graças de Luna, M.,... Mattos-Guaraldi, A.-L. (2015). Corynebacterium diphtheriae putative tellurite-resistance protein (CDCE8392_0813) contributes to intracellular survival in human epithelial cell and lethality of Caenorhabditis elegans. Memorias Do Instituto Oswaldo Cruz, 110, 662-668. https://dx.doi.org/10.1590/0074-02760140479
Trost, E., Al-Dilaimi, A., Papavasiliou, P., Schneider, J., Viehoever, P., Burkovski, A.,... Tauch, A. (2011). Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors. Bmc Genomics, 12, 383. https://dx.doi.org/10.1186/1471-2164-12-383
Calabria A, J., Vasconcelos, W.L., Daniel, D.J., Chater, R., Mcphail, D.S., & Boccaccini, A.R. (2010). Synthesis of sol–gel titania bactericide coatings on adobe brick. Construction and Building Materials, 24, 384-389. https://dx.doi.org/10.1016/j.conbuildmat.2009.08.020
Trost, E., Ott, L., Schneider, J., Schroeder, J., Jaenicke, S., Goesmann, A.,... Tauch, A. (2010). The complete genome sequence of Corynebacterium pseudotuberculosis FRC41 isolated from a 12-year-old girl with necrotizing lymphadenitis revealed insights into gene-regulatory networks contributing to virulence. Bmc Genomics, 11, 728. https://dx.doi.org/10.1186/1471-2164-11-728
Calabria, J.A., Vasconcelos, W.L., & Boccaccini, A.R. (2009). Microstructure and chemical degradation of adobe and clay bricks. Ceramics International, 35, 665-671. https://dx.doi.org/10.1016/j.ceramint.2008.01.026
Kannan, S., Götz-Neunhoeffer, F., Neubauer, J., Rebelo, A., Valério, P., & da Fonte Ferreira, J.M. (2009). Rietveld structure and in vitro analysis on the influence of Magnesium in Biphasic (Hydroxyapatite and beta-Tricalcium phosphate) mixtures. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 90, 404-411. https://dx.doi.org/10.1002/jbm.b.31299
Braga, F.C., Kreis, W., & Braga de Oliveira, A. (1998). Effect of Digitalis lanata matrix composition on the lanatoside C partition coefficient and its consequence on rotation locular counter-current chromatography efficiency. Journal of Chromatography A, 822, 37-44. https://dx.doi.org/10.1016/S0021-9673(98)00559-7

Last updated on 2016-13-04 at 08:16