[18F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana

Speicher T, Bastian MB, Christofyllakis K, Rosar F, Ezziddin S, Burgard C (2025)

Publication Type: Journal article

Publication year: 2025

Journal

Diagnostics MDPI

Book Volume: 15

Article Number: 862

Journal Issue: 7

DOI: 10.3390/diagnostics15070862

Abstract

We present an 18F-fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) scan of a 27 y/o patient with long-standing significant B symptoms, diffuse bone pain, increased inflammation parameters, and polydipsia revealing multiple FDG-avid osteolytic lesions of the axial skeleton including a vertebra plana of T7 and paraosseous soft tissue lesions. A CT-guided biopsy confirmed the diagnosis of Langerhans cell histiocytosis (LCH). This case highlights the importance of considering LCH in young patients with vertebral collapse and underscores the role of PET/CT imaging in establishing an accurate diagnosis.

Involved external institutions

Universitätsklinikum des Saarlandes (UKS) DE Germany (DE)

How to cite

APA:

Speicher, T., Bastian, M.B., Christofyllakis, K., Rosar, F., Ezziddin, S., & Burgard, C. (2025). [18F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana. Diagnostics, 15(7). https://doi.org/10.3390/diagnostics15070862

MLA:

Speicher, Tilman, et al. "[18F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana." Diagnostics 15.7 (2025).

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