Quantifying Anatomical Bias in Coronary Segmentation: Why Your Model Prefers the LCA More Than the RCA

Baumgart S, Deubner N, Kist A (2026)


Publication Type: Conference contribution

Publication year: 2026

Journal

Publisher: Springer Science and Business Media Deutschland GmbH

Pages Range: 70-75

Conference Proceedings Title: Informatik aktuell

Event location: Lübeck DE

ISBN: 9783658510992

DOI: 10.1007/978-3-658-51100-5_12

Abstract

Deep learning-based segmentation of coronary arteries in X-ray angiography supports stenosis assessment via the Quantitative Flow Ratio. However, traditional metrics like the Dice coefficient neglect howimage acquisition parameters, particularly vessel type and projection angle, affect model accuracy. This study evaluated four U-Net-based models (vanilla U-Net, nnUNet, and U-Nets using MobileNetV2 or InceptionResNetV2 as encoders) on 599 patients covering twelve common projection angles. Results show that projection angles, including vessel overlap, have a stronger impact on segmentation quality than vessel type. InceptionResNetV2 achieved the highest overall Dice scores, while nnU-Net better captured capillaries and catheters. Distal branches remained challenging for all models. Our findings highlight the need to consider projection-angle diversity and segment-level evaluation in datasets and benchmarks to ensure clinically reliable coronary segmentation.

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How to cite

APA:

Baumgart, S., Deubner, N., & Kist, A. (2026). Quantifying Anatomical Bias in Coronary Segmentation: Why Your Model Prefers the LCA More Than the RCA. In Heinz Handels, Katharina Breininger, Thomas Deserno, Andreas Maier, Klaus Maier-Hein, Christoph Palm, Thomas Tolxdorff (Eds.), Informatik aktuell (pp. 70-75). Lübeck, DE: Springer Science and Business Media Deutschland GmbH.

MLA:

Baumgart, Selina, Nikolas Deubner, and Andreas Kist. "Quantifying Anatomical Bias in Coronary Segmentation: Why Your Model Prefers the LCA More Than the RCA." Proceedings of the Bildverarbeitung für die Medizin Workshop, BVM 2026, Lübeck Ed. Heinz Handels, Katharina Breininger, Thomas Deserno, Andreas Maier, Klaus Maier-Hein, Christoph Palm, Thomas Tolxdorff, Springer Science and Business Media Deutschland GmbH, 2026. 70-75.

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